Acrobiosystems Stock – Twist Bioscience developed a proprietary semiconductor-based synthetic DNA production process with a high-throughput silicon platform that allows us to miniaturize the chemistry required for DNA synthesis.
This provides our customers with time and cost savings in their workflow. Researchers can access quality tools for libraries with more accurate NGS, highly customizable gene synthesis at scale to fit any workflow, more accurate genomic screens requiring fewer resources, and optimized search power because each variant is synthesized directly.
Twist’s technical support team is available to help you tackle your biggest research challenges. Hear what our customers have to say:
A Broad And Potent Neutralization Epitope In Sars Related Coronaviruses
“Twist’s technical support team helped us discuss and design our probe panel. It’s never been off-the-shelf, take-it-a-live-it with Twist. They’ve developed their methyl. seq product line further, We shared information to get the best results. That’s what I love about working with Twist.”
Accelerating antibody discovery for infectious disease genes. Antibody discovery for infectious disease genes Discover how high-throughput gene synthesis in Twist is used to develop candidate antibody therapies in less than 60 days.
Baker Lab at the University of Washington: Designing Proteins to Revolutionize Biotechnology Baker Lab at the University of Washington: Designing Proteins to Revolutionize Biotechnology Oligo Pools Oligo pools allow the Baker Lab to screen thousands of potentially viable designs that could never be engineered for proteins. exists in nature.
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2020 & 2021 Fast 500 Technology Companies List We’re Proud of Our Products + Customer Service View Article Human TSLP, His Tag (TSP-H52Hb) Expressed from Human 293 Cells (HEK293). It contains AA Tyr 29 – Gln 159 (accession number Q969D9-1).
The calculated MW of the protein is 16.8 kDa. Glycosylation causes the 8 kDa and 14-20 kDa proteins to migrate in the reducing (R) state (SDS-PAGE).
Human TSLP, its tag on SDS-PAGE under reduced (R) conditions. Gels were stained with Coomassie blue. Protein purity is more than 90%.
Immobilized human TSLP, its tag (cat. no. TSP-H52Hb) at 0.5 μg/mL (100 μL/well) monoclonal anti-human TSLP antibody with a linear range of 0.2-4 ng/mL (QC) can bind human IgG2. ) has been tested).
Acrobiosystems: Where Proteins And Innovation Advance Biomedicine
Captured human TSLP, His tag (cat. no. TSP-H52Hb) can bind to human TSLP R, Fc tag (cat. no. TSR-H525a) by anti-His antibody on a CM5 chip with an affinity constant of 1.81 nM, as determined by the SPR Analysis (Biacore T200) (routine test).
A monoclonal anti-human TSLP antibody (human IgG2) captured on the CM5 chip via an anti-human IgG Fc antibody surface can bind the human TSLP protein, His tag (cat. no. TSP-H52Hb) with an affinity constant of 5.47 pM. SPR analysis (Biacore T200) (routine test).
The monoclonal anti-human TSLP antibody loaded on the AHC biosensor, human IgG2 can bind human TSLP, its tag (cat. no. TSP-H52Hb) with an affinity constant of 0.263 nM as determined in BLI analysis (ForteBio Octet Redut96). tested).
TSLPR (Luc) HEK293 reporter cells were stimulated with serial dilutions of human TSLP protein (, Cat. no. TSP-H52Hb). The maximum induction fold was approximately 45.15 (routinely tested).
Investigational Medical Products For Rare Diseases: Ethical Concerns And Unresolved Issues With Expanded Access
Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases and is widely expressed by epithelial cells. Human TSLP cDNA encodes a precursor protein of 159 amino acids (aa) with a 28 aa signal sequence (4, 5). Deletion of human TSLP develops central tolerance, enhances epithelium-induced class switching, induces atopic diseases, and maintains an intestinal non-inflammatory environment. Among the various cells that respond to human TSLP, CD11c+ dendritic cells are the most clearly characterized target cells.
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